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Title: Genome sequence of the lignocellulose degrading fungus Phanerochaete chrysosporium strain RP78

Source: NATURE BlOTECHNOLOGY VOLUME 22 NUMBER 6 JUNE 2004

Author(s)Martinez, Diego; Larrondo, Louis F.; Putnam, Nik; Gelpke, Maarten D. Sollewijn; Huang, Katherine; Chapman, Jarrod; Helfenbein, Kebin G.; ramaiya, Preethi; Detter, J. Chris; Larimer, Frank; Coutinho, Pedro M.; Henrissat, Bernard; Berka, Randy; Cullen, Dani

Publication Year: 2004  View PDF »

Category: Journal Articles

Abstract: White rot fungi efficiently degrade lignin, a complex aromatic polymer in wood that is among the most abundant natural materials on earth. These fungi use extracellular oxidative enzymes that are also able to transform related aromatic compounds found in explosive contaminants, pesticides and toxic waste. We have sequenced the 30-million base-pair genome of Phanerochaete chrysosporium strain RP78 using a whole genome shotgun approach. The P. chrysosporium genome reveals an impressive array of genes encoding secreted oxidases, peroxidases and hydrolytic enzymes that cooperate in wood decay. Analysis of the genome data will enhance our understanding of lignocellulose degradation, a pivotal process in the global carbon cycle, and provide a framework for further development of bioprocesses for biomass utilization, organopollutant degradation and fiber bleaching. This genome provides a high quality draft sequence of a basidiomycete, a major fungal phylum that includes important plant and animal pathogens.

Keywords: Wood-destroying fungi, wood-decaying fungi, genome sequences, Phanerochaete chrysosporium

Publication Review Process: Informally Refereed (Peer-Reviewed)

File size: 502 kb(s)

Date posted: 05/17/2010

This publication is also viewable on Treesearch:  view
RITS Product ID: 22127
Current FPL Scientist associated with this product
Cullen, Daniel
Research Microbiologist
  

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